2D and 3D
Circulating Tumor Cells Culture

Cell culture application

Optimizing circulating tumor cells culture culture with 2D and 3D techniques

ScreenCell technology offers researchers an innovative solution for the isolation and 2D and 3D circulating tumor cells culture, directly from patients’ blood.

By enabling the circulating tumor cells culture, ScreenCell facilitates the in-depth study of their biological behavior, proliferation and molecular characteristics.

This approach is a major asset for basic research, providing a unique model to explore the mechanisms of tumor progression, cancer heterogeneity and the identification of new therapeutic targets.

comparatif culture de cellules tumorales circulantes

2D cell culture on MB isolation support

ScreenCell technology plays a key role in the success of this technique by ensuring the viability and proliferative and invasive potential of isolated CTCs. The cells of interest are captured alive, then cultured under optimized conditions to promote their expansion and ex-vivo characterization.

With this method, it is possible to analyze specific subpopulations of CTCs, while preserving their ability to model complex biological phenomena.

ScreenCell kits for
2D and 3D circulating tumor cells culture

ScreenCell MB kit

MB

Blood sample < 4 hours

Isolated living cells on the isolation support

circulating tumor cells culture

LCD

Blood sample < 4 hours

Living cells detached
from the suspended isolation support

Little by little, the CTCs are making their nest

Day 7 of CTCs cell culture

circulating tumor cells culture

Day 23 of CTCs cell culture

2d circulating tumor cells culture

ScreenCell devices have been specifically designed to provide a favorable microenvironment for the isolation and expansion of CTCs, opening unique perspectives to study the mechanisms of metastasis and resistance to anticancer treatments.

In addition, isolated cells can also be detached from their membrane support and suspended, providing additional flexibility for their analysis. This alternative allows the examination of single cells, as well as the exploration of advanced applications such as 3D circulating tumor cells culture.

Tell us about your project

Are you interested in establishing a fundamental or clinical research project focused on circulating tumor cells (CTCs) or liquid biopsy ?

Share your project details with us, and we will be delighted to assist you in bringing it to fruition.

Liquid biopsy for
enhancing patient care
through reliable CTC analysis

Webinar

Circulating Tumor Cell Analysis :
a new workflow combining ScreenCell® Technology
with Stilla Crystal Digital PCR®

Tuesday, April 8, 2025
04:00 PM CET
Wednesday, April 9, 2025
03:00 PM CST
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